Yes, and insulin resistance (beta cell organelle dysfunction) is associated with deficient autophagy Full Free ArticleSo low insulin sensitivity may be a factor in inhibiting autophagy right ?RRM wrote:Autophagic proteolysis and sirtuin activity are downregulated by the insulin signaling pathway.
There are 'anomalies' in autophagy responses in (type 1 and 2) diabetes. Mellor KM et al
Defective autophagy causes insulin resistance Full Free Article
Both acute and chronic. Both aerobic and anaerobic. From the various studies i read, it may be hours of walking or short bursts of intense activity,What sort of exercise ? Aerobic exercise ? Anaerobic exercise ? Is walking also evoking autophagy ?Hence caloric restriction and exercise (both catabolic) evoke autophagy.
and anything in between.
Example: During 80 minutes, mice either had to run 900 meters or at 75% of maximum runnning capacty. Full Free Article
The only thing that is essential, is the induction of low levels of energy (AMP to ATP) in muscle cells,Hardie DG
induced by both exercise and caloric restriction Full Free Article,
which can also be achieved by walking.
I created a preliminary Wai Wiki page for autophagy
Of course, i still need to add a lot of info.