Aytundra wrote:What about this:
If
Kavanagh et al were the police they will put fructose in jail because of their primate study.
Its a study about Hepatic steatosis (accumulation of fat in the liver). Hepatic steatosis is associated with the development of diabetes and cardiovascular disease.
The funny thing is:
In population studies (the proof is in the pudding), fructose intake (from veggies/fruits) is associated with
less diabetes and stroke.
Fructose will only end up as liver-fat once the conversion of fructose in liver-glycogen has been completed.
This liver-glycogen is 'spare glucose' for maintaining the blood-glucose level at the right level.
If you keep on consuming fructose after all liver-glycogen (~400 kcal) has been replenished, the rest is stored as liver-fat.
If you susbsequently are going to use that glycogen to lost blood-glucose, and that fat to replenish blood-fatty acid levels, everything is absolutely fine.
That is the whole purpose of liver-glycogen and liver-fat.
Only if you do not susbsequently use that stored liver-fat, liver-fat may accumulate.
Fructose and glucose go different pathways.
The intake of glucose is easily monitored by you by sensing your blood-glucose level.
Its different for fructose, as the main purpose of fructose is replenishment of liver-glycogen.
If fructose consumption is not coupled with glucose consumption, you may lack the feedback from blood-glucose sensing to control your fructose intake.
In fruit and veggies (and in table sugar), fructose is coupled with glucose.
On the other hand, even if fructose and glucose are uncoupled, you may still want to wait having more food until your blood glucose level goes down due to a lack of liver-glycogen, which makes it safe to consume more fructose.
About
the study:
Both the HFr diet and the control diet contain 69 energy% carbs.
An essential difference is that the Hfr diet contains 17 energy% fat and the control diet 13 energy% fat. (i am surprised that they did that)
Other studies have shown that its exactly the combination of sugars and fat that makes you gain weight more readily.
So, one may also attribute the accumulation of liver-fat to the higher level of carb-fat combination.
It would be interesting to compare the effects of consuming grains and tubers (starch>glucose) versus fruits and veggies (glucose, fructose).